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MK2866 (Ostarine) Abstract

 

Ostarine, also known as MK-2866, is in class of drugs called SARMS, which stands for selective androgen receptor modulators.

Ostarine is selective in that it binds only to bone and muscle androgen receptors, which prevents things like prostate issues or hair loss or any of the other nasty side effects anabolic steroids can result in.

This experimental drug was developed in 2009 by the company Gtx in an effort to fight muscle wasting diseases. As with many bodybuilding drugs, osta accidentally turned out to be a fantastic side effect free tool for fitness enthusiasts, bodybuilders and those with nagging injuries they’ve given up hope of healing.

 

MK2866 (Ostarine) Application

 

Ostarine is the most anabolic of any SARMS, making its first and foremost use for wanting to gain lean muscle. The gains in total weight will not be comparable to bulking steroids, however the total gains will almost entirely be lean muscle.

Ostarine would primarily fit into a cutting protocol for the maintenance of muscle mass while reducing calories. One of the most disheartening outcomes of cutting is the loss hard earned muscle mass. The drop in metabolic rate and hormone levels (T3, etc) with the lack of calories is a perfect catabolic environment for loss of muscle tissue.

Recomping is where ostarine truly shines. The recomping effect of losing fat and gaining muscle at the same time is what the majority of users are looking for. Trying to achieve this when you are not absolutely new to training is extremely difficult.

The effects of ostarine translate to anabolism in bone and skeletal muscle tissue, which means it could be used in the future for a variety of uses, such as osteoporosis and as a concurrent treatment with drugs that reduce bone density. Therefore it has great application as a compound to use for rehabilitation of injuries, in particular bone and tendon related injuries.

 

MK2866 (Ostarine) Traits

 

As a SARM, Ostarine binds directly to the androgen receptors. While anabolic steroids also bind to androgen receptors, SARM’s cannot convert to DHT or estrogen. Officially belonging to a group of drugs, Ligand, MK 2866’s only purpose is direct anabolic activity. This SARM can be used for muscle growth or muscle preservation (diet dependent).

Ostarine, like anabolic steroids, will increase protein synthesis as well as nitrogen retention. However,  unlike anabolic steroids, it will do so without any DHTor estrogen conversion.

While no direct estrogen conversion is present in terms of aromatase activity, mild increases in estrogen levels have been shown. This is perhaps why Ostarine has been shown to be good for joint health and healing. Estrogen often gets a bad wrap, but some is needed for good health and physical performance. It is,however, the direct binding to the receptor that is most important as it not only promotes anabolism, it alters the gene sequence directly at the receptor site; in fact, it is highly tissue specific, muscle and bone