Losing Weigh Gw501516 Sarms Raw Powder Cardarine sarms bodybuilding supplements CasNO.317318-70-0

GW501516 Product details

Product Name: 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid
Synonyms: 2-(4-((2-(4-(TRIFLUOROMETHYL)PHENYL)-5-METHYLTHIAZOL-4-YL)METHYLTHIO)-2-METHYLPHENOXY)ACETIC ACID;2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic Acid;Methyl-methyl-trifluoromethylphenyl -thiazolyl-methylsulfanyl-phenoxy-acetic Acid;2-(4-((2-(4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylthio)-2-methylphenoxy)acetic acid;GW 1516;2-(2-methyl-4-((5-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)methylthio)phenoxy)acetic acid;GW501516, Free Acid;GSK-516
CAS: 317318-70-0
MF: C21H18F3NO3S2
MW: 453.5
Purity:99%
Appreance:Chemical Properties White Solid
Grade:Pharmaceutical Grade

Usage :For obesity, diabetes, dyslipidemia and cardiovascular disease
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.

GW501516 Description

KEY WORDS:Fat loss, improve endurance,no side effect,bodybuilder,cure for obesity plus helps retain lean mass,increases muscle mass.

Cardarine (GW-501516) is grouped in the category of SARMS, however in structure and definition, it is a PPAR modulator. As a PPAR modulator, it activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue. GW-501516 possesses abilities to reverse metabolism problems by stimulating fatty acid oxidation. It is considered a strong treatment for obesity and other related conditions.

GW501516 is the name of a Glaxo Wellcome drug (the GW stands for the company and the number is that of the product). It is also known as GW-501,516, GW1516, GSK-516). It is a PPARδ receptor agonist that was not taken further than clinical trials. As such it is banned in sport. It fits in a number of places on the list, including specifically as “a peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (e.g. GW501516)”. But it would also come under WADA’s new catch all “non approved substances” section that aims to stop any unlicensed drug being used by athletes.

GW501516 (also known as GW-501,516, GW1516, GSK-516) is a PPAR& receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.

In 2007 research was published showing that high doses of GW501516 given to mice dramatically improved their physical performance; the work was widely discussed in popular media, and led to a black market for the drug candidate and to its abuse by athletes as a doping agent.