Sodium L-Triiodothyronine also known as T3,it is a thyroid hormone which affects almost body physiological process.T3 contains three atoms of iodine and is formed by the coupling of one molecule of DIT with one molecule of monoiodotyrosine.Production of T3 and its prohormone thyroxine is activated by thyroid-stimulating hormone.As concentrations of decrease, the anterior pituitary gland increases TSH production of and control system stabilizes the amount of thyroid hormones that are in the bloodstream.T3 responsible for regulating the uptake of various nutrients into cells in human body,and effectively become utilized for the production and consumption of energy.
It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.T3 increases the basal metabolic rate and, thus, increases the body’s oxygen and energy consumption. The basal metabolic rate is the minimal caloric requirement needed to sustain life in a resting individual. T3 acts on the majority of tissues within the body, with a few exceptions including the spleen and testis. It increases the production of the Na+/K+ -ATPase and, in general, increases the turnover of different endogenous macromolecules by increasing their synthesis and degradation.
Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to T3. As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body’s sensitivity to catecholamines by permissiveness.
The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.It usually used as treatment of depressive disorders and as a fat loss supplement.





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