name: MGF (Mechano growth factor) (IGF- IEC)
specification: 2mg/vial, 10vials/box
MGF (also known as IGF-1Ec) is a splice variant of the IGF gene, which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for the growth of adult muscle. MGF is produced naturally when muscle fibers are broken down through resistance (weight training). MGF stimulates muscle growth, creates new muscle fibers, promotes muscle recovery, promotes nitrogen retention, and increases protein synthesis.
In studies where MGF was administered intramuscularly, there was a 20% increase in the weight of the injected muscle fibers within 2 weeks. In further studies, it took 4 months for IGF to cause a 25% increase in muscle mass. MGF was found to be more potent than IGF-1 in rapid muscle growth. Fat loss and strength increases are not typically seen with MGF’s use (as they are with IGF-1 use).
MGF is a prime candidate for gene doping for the enhancement of athletic performance. MGF can produce rapid increases in muscle and strength, giving it considerable therapeutic and doping potential. It has potential for optimizing physical training.
Let’s start with an explanation of Mechano Growth Factor (MGF) and what it does. The muscle insulin-like growth factor-I (IGF-I) mRNA splice variant (IGF-IEc) has been identified in rodents. IGF-IEc, also called mechano growth factor (MGF), has been found to be up-regulated by exercise or muscle damage. Growth hormone (GH) is the principal regulator of IGF-I expression in several tissues, including skeletal muscle.
MGF is derived from IGF-I, but its sequence differs from the systemic IGF-I produced by the liver. MGF is expressed by mechanically overloaded muscle and is involved in tissue repair and adaptation. It is expressed as a pulse following muscle damage and is apparently involved in the activation of muscle satellite (stem) cells. These donate nuclei to the muscle fibers that are required for repair and for the hypertrophy processes, which may have similar regulatory mechanisms.




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