Product Name: Mechano Growth Factor, MGF
MF: C121H200N42O39
MW: 2888.16
Purity: 99%
Specification: 2mg/vial
Appearance: White Lyophilized Powder
Grade: Pharmaceutical Grade
2 kinds of MGF splice variants of IGF
Mechano Growth Factor (MGF), also known as IGF-1E, is a growth factor/repair factor that is derived from exercised or damaged muscle tissue. It’s called MGF, as IGF-IEa is a bit of a mouthful and harder to identify amongst the other IGF variants.
IGF-1Ec: This is the first phase release of the IGF splice variant, and it appears to stimulate satellite cells into activation. This is the closest variant to synthetic MGF. When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene is released and is differentially spliced during the body’s response. Initially, it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. This, in turn, allows the activation of extra undamaged nuclei to grow new muscle fibers and tissue. The appearance of MGF also initiates the upregulation of new protein synthesis.
IGF-1Ea: After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis. It is the secondary release of IGF from the liver, and it’s far less anabolic and shorter acting.
The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair, is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an injectable peptide, and it has been anecdotally shown that injecting it will cause a response in the area, resulting in localized muscle growth.
MGF is a splice variant of the IGF gene, which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for the growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water-based and, when administered intramuscularly, travels into the bloodstream. MGF is only stable in the bloodstream for a few minutes.
In bodybuilding, this drug is used to accelerate muscle growth. Other effects of the drug include a decrease in fat mass of the body, an increase, improvement in immune defense and skin, bone strengthening, a lowering of cholesterol level, and accelerated recovery. Those who administered MGF declared that they experienced no side effects, which frequently occur with the use of other drugs for gaining body mass.




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