Anabolic Androgenic Steroids (AAS) are a type of steroid hormone developed to promote anabolism; the process of building and synthesizing molecules in the body. All AAS are derivatives of the steroid hormone testosterone. AAS were designed to improve upon testosterone’s anabolic effect while minimize unwanted androgenic effect in treating patients with catabolic medical conditions. The anabolic effect of AAS are to promote protein synthesis through the efficient use of amino acids, prevent protein breakdown, retain nitrogen and build skeletal muscle. Androgenic effects are those related to puberty such as male pattern baldness, deepening of the voice, facial hair growth, increase sebaceous gland excretion. AAS, such as Anavar, have a high anabolic activity (high anabolic: androgenic ratio of 10:1) compared to testosterone (anabolic: androgenic ratio of 1:1).
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Oxandrolone a unique oral anabolic steroid hormone that is also known as Anavar. Anavar was first synthesized in 1962 and has been used in the medical treatment of catabolic disorders for over 30 years. Anavar is unique because it has great oral bioavailability (can be taken my mouth) and is resistant to liver metabolism. Anavar also does not get aromatized into estrogen compared to testosterone. The primary use of Anavar is to prevent frailty and the loss of muscle mass due to aging (sarcopenia) and other related catabolic clinical disorders such as HIV -related muscle waiting, severe burn injuries, trauma after surgery and hepatitis.
Anavar has been shown to:
1) Decrease visceral fat and total body fat
2) Increase protein synthesis in skeletal muscle
3) Increase dietary energy and protein intake
4) Increase nitrogen retention
5) Increase muscle function, growth, strength and physical activity level
6) Substitute for the natural loss of androgen and estrogen hormones




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