China 99% Purity Toremifene Citrate Fareston raw powder anti estrogen products
Basic Information
Other Name:Fareston
MF:C32H36ClNO8
MW:598.08
Melting Point:160-162°C
BP:146-148°C
Density:1.045g/cm
Refractive Index:1.416-1.418
Storage Temp:-20°C Freezer
Half Life:Around 5 Days
Appearance:White To Off-White Solid
High Light:anti estrogen supplements, anti estrogen products
Toremifene citrate is a member of a category, family, and class of drugs that are known as SERMs (Selective Estrogen Receptor Modulators). SERMs fall under an even broader category of drugs that are known as anti-estrogens, and the cousin family of SERMs (that also fall under anti-estrogens) are aromatase inhibitors, commonly abbreviated as AIs. SERMs include compounds such as Nolvadex and Clomid (Clomiphene Citrate). Aromatase inhibitors (AIs) include compounds such as Arimidex ) Aromasin, (Femara). Although the two fall under the category of anti-estrogens, they are both sub-categories that branch off into their own families, as SERMs and AIs differ greatly in their mechanism of action within the human body concerning how they control or block Estrogen. There has been much misunderstanding and misconception in previous decades as to what each of these do, and this should always be first clarified to the reader before describing Toremifene.
Toremifene citrate functions as a selective estrogen receptor modulator (SERM) with both agonistic and antagonistic properties. Here are its main functions and traits:
- Antiestrogenic Effects: Toremifene citrate acts as an antagonist by binding to estrogen receptors in target tissues, such as breast tissue. By blocking the binding of estrogen to these receptors, it inhibits the proliferative effects of estrogen on breast cancer cells, thereby slowing down or stopping their growth.
- Estrogenic Effects on Bone: Toremifene citrate has estrogen-like effects on bone tissue. It helps maintain or improve bone mineral density, which is particularly beneficial for postmenopausal women who are at a higher risk of developing osteoporosis.
- Breast Cancer Treatment: Toremifene citrate is primarily used in the treatment of estrogen receptor-positive breast cancer. It is often prescribed as adjuvant therapy after primary treatment (such as surgery or radiation) to reduce the risk of cancer recurrence. It may also be used in advanced or metastatic breast cancer cases.
- Reduction of Breast Cancer Risk: Toremifene citrate has also been studied for its potential to reduce the risk of developing breast cancer in high-risk individuals. It may be considered as a preventive option for women with a strong family history of breast cancer or certain genetic mutations associated with the disease.
- Regulation of Lipid Profiles: Toremifene citrate has been shown to have favorable effects on lipid profiles by reducing total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides while increasing high-density lipoprotein (HDL) cholesterol levels. This can contribute to cardiovascular health.
It’s important to note that while toremifene citrate has demonstrated efficacy in breast cancer treatment and prevention, its use should be under the guidance of a healthcare professional. They can assess individual circumstances, monitor treatment progress, and manage any potential side effects.
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