Product Name: TB500
Alias: Thymosin beta 4 acetate
CAS: 77591-33-4
MF: C212H350N56O78S
MW: 4963.49
Purity (HPLC): 95%min
Single Impurity (HPLC): 2.0%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): >= 80.0%
Water Content(Karl Fischer): <= 5.0%
Acetate Content (HPIC): <= 15.0%
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
Appearance: White powder
Specification: 2mg/vial,10vials/box
TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human and animal cells. The main purpose of this peptide is to promote healing. It also promotes creation of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons, ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher concentration where tissue has been damaged. This peptide is also a very potent anti-inflamatory agent.
One of TB-500 key mechanisms of action is its ability to regulate the cell-building protein – Actin. Of the thousands of proteins present within human cells, actin represents roughly 10% of the total. It is thus a vital component of cell structure and movement.
Thymosin Beta-4 is a protein which consists of 43 amino acids and is encoded by the gene TMSB4X in the human body. It has been studies in numerous clinical trials. Research has shown that if the thymosin beta-4 peptide is used after a heart attack it can reactivate cardiac progenitor cells to repair damaged heart tissue.
Thymosin beta-4 is a very large molecule. In fact, it is so large that it cannot fit entirely into the receptor. Different sections of the molecule have different activities. TB-500 is the part of thymosin beta-4 hormone which promotes the most useful effects. For medical applications it is more practical to use the TB-500 instead of the entire Thymosin Beta-4 protein.
Thymosin beta 4 antibodies, antibody of Thymosin beta 4 manual high degree of specificity, immunohistochemica is use of this principle.First to pick up the tissues or cells of certain chemicals, as antigen or hapten, after immune animals get specificity of the antibodies, and the further of antibody to detect tissue or cell antigen of the same kind of material.Because of antigen and antibody of complex is a colorless, therefore also must use histochemistry method can display the antigen antibody combining site by its reach to the unknown antigen in the tissues or cells are qualitative, positioning and quantitative research.
TB-500 is an injectable peptide drug which can be used to promote healing, enhance range of motion in cases of injury, or reduce pain in case of injury by reducing inflammation. As yet its human use has been relatively uncommon and limited to individuals who like to experiment. Use in race horses has been more widespread, though it’s not a prescription veterinary drug.





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