Mk-677 SARMs Raw Powder HPLC 99.5% Mk677 For Muscle Building Ibutamoren CasNO.159752-10-0

MK-677（Ibutamoren）Description

1. Ibutamoren (MK-677, L-163,191) acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin.
2. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels.
3. MK-677 is currently under development as a potential treatment for reduced levels of these hormones which make it a promising therapy for the treatment of frailty in the elderly.
4. MK-677 also alters metabolism of body fat and so may have application in the treatment of obesity
5. Mk-677 is an orally administrated growth hor secretagogue originally developed by Reverse Pharmacology. A secretagogue is the term for a substance that chemically signals for the pituitary gland to secrete growth hormone.
6. MK-677 could be compared to peptides like GHRP-6 or Ipamorelin, only it doesn’t require any injections nor does it have any side effects like GHRP-6.
7. This GHS (Growth Hormone Secretagogue) was developed in an aim to combat such conditions as muscle wasting, obesity and osteoporosis. It was also targeted towards treatment of elderly hip fracture patients, so there are a myriad of studies done on safety.

Health Benefits of MK-677（Ibutamoren）

1. Ibutamoren (MK-677)Helps Build Muscles Ibutamoren is frequently used as an anabolic substance, to increase lean body mass i.e. create bigger muscles. It is orally active and can be taken once a day. These are all benefits compared with other growth GH hormone stimulators. In healthy obese men, a two-month treatment with ibutamoren increased lean mass, and transiently increased basal metabolic rate (BMR) .
2. Ibutamoren (MK-677)Reduce Muscle Wasting In food-deprived healthy volunteers, ibutamoren reversed diet-induced protein loss , that could cause muscle wasting. In elderly patients with hip fracture, ibutamoren improved gait speed, muscle strength and reduced the number of falls .
3. Ibutamoren (MK-677)Increases Bone Density Growth GH hormone increases bone turnover and eventually bone density . However, because of the increased turnover in subjects treated with growth GH hormone, bone density can initially decrease before increasing . Basically, it takes time (> 1 year) to see the bone density increase. In healthy obese male volunteers, ibutamoren increased bone turnover . In elderly adults, ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover . In post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis .