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Ghrelin not only to promote the release of growth, but also has other biological effects, such as mediation feeding and energy metabolism, cardiovascular function, control gastrointestinal function and inhibition of tumor cell proliferation and so on . Recent studies have shown that serum ghrelin concentration was positively correlated with BMD, so ghrelin may be involved in the metabolism of bone tissue, affecting the function of osteoblasts

GHRP2 is a synthetic ghrelin analogue. Like ghrelin, it stimulates release of endogenous from somatotropes in the anterior pituitary; also like ghrelin, it is synergistic with endogenous releasing-ormone (GHRH) as well as with synthetic GHRH analogues such as Sermorelin or GRF(1-29). Whereas GHRP2 and other ghrelin analogues increase the number of somatotropes involved in the GH pulse by inhibiting somatostatin, GHRH increases the pulse amplitude per pituitary cell or somatotrope by other means. Unlike ghrelin, GHRP2 is not lipogenic meaning it does not induce fat storage. While ghrelin has a very important role in hunger, GHRP2 as an analog of ghrelin does not increase appetite significantly. GHRP2 is synergistic with GHRH due to secondary actions on hypothalamic neurons. The quantity of GH released by a living mammal to which GHRP2 and GHRH are administered exceeds the combined release of each compound when measured when taken alone.

GHRP – 2 is a true hGH secretagogue. Which means it stimulates the body’s own secretion of hGH as explained in the study below. Human Growth hormone has been shown in studies to promote lean body mass and reduce adiposity (fat). ‘The group compared ITT to stimulation with GH releasing peptide 2 (GHRP-2).

GHRP – 2,The synthetic hexapeptide, also named pralmorelin, is derived from a metenkephalin peptide. It is the most potent of the family of synthetic GH stimuli known in humans and acts via the endogenous ghrelin receptor (12).

GHRP – 2,As these receptors have been identified both in the hypothalamus and the pituitary, GHRP-2 action may not be restricted to the pituitary.It has been reported that growth hormone (GH)-releasing peptide-2 (GHRP-2), a ghrelin receptor agonist, has an anti-inflammatory effect.

GHRP-2 is short for Growth Hormone Releasing Peptide 2, which basically refers to an hgH secretagogue, according to some research studies on rats, it can effectively increase the amount of natural secretion of hgH in the test subjects body and secrete it while stimulating the pituitary gland at the same time.