Sildenafil, sold as Viagra and other trade names, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. Its use for sexual dysfunction in women is not clear.
Common side effects include headaches and heart burn, as well as flushed skin. Caution is advised in those who have cardiovascular disease. Rare but serious side effects include prolonged erections, which can lead to damage to the penis, and sudden-onset hearing loss. Sildenafil should not be taken by people who take nitrates such as nitroglycerin, as this may result in a severe and potentially fatal drop in blood pressure.
It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.
It was originally discovered by Pfizer scientists Andrew Bell, David Brown, and Nicholas Terrett.[2][3] Since becoming available in 1998, sildenafil has been a common treatment for erectile dysfunction; its primary competitors are tadalafil (Cialis) and vardenafil (Levitra).
Viagra works for long duration in quick time as it stays inyour system for up to 36 hours. When a man is sexually excited, his bodynormally reacts by increasing the blood flow to his penis. This results into anerection. ED occurs when the blood flow to the penis is diminished or lessened, this can be caused by a number of medical conditions. After Cialis Tadalafil istaken, your body starts responding within 30 minutes to an hourmaking it easierto achieve an erection. Cialis will remain active within your body for following36 hours, so achieving and maintaining an erection within this period will beeasy.
Viagra has proven to improve erectile function in most men,even when men suffer with mild, moderate or severe erectile dysfunction. Cialishas shown great promise with satisfactory results under clinical trials. Cialishelps to boost your confidence by improving your ability with power to maintainhard and strong erection, which will give you the ultimate satisfaction duringsexual intercourse.Cialis allows you to respond to your partner at the rightmoment.



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